Publications

Bobkov, G.O.M., Huang, A., van den Berg, S.J.W., Mitra, S., Anselm, E., Lazou, V., Schunter, S., Feederle, R., Imhof, A., Lusser, A., Jansen, L.E.T., and Heun, P. (2020). Spt6 is a maintenance factor for centromeric CENP-A. Nature communications 11, 2919. PDF

Medina-Pritchard, B., Lazou, V., Zou, J., Byron, O., Abad, M.A., Rappsilber, J., Heun, P., and Jeyaprakash, A.A. (2020). Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. EMBO J 39, e103234. PMC7110144 PDF

Scacchetti, A., Schauer, T., Reim, A., Apostolou, Z., Campos Sparr, A., Krause, S., Heun, P., Wierer, M., & Becker, P. B. (2020). Drosophila SWR1 and NuA4 complexes are defined by DOMINO isoforms. eLife, 9, e56325. https://doi.org/10.7554/eLife.56325. PMID: 32432549; PMCID: PMC7239659. PDF

Roure, V., Medina-Pritchard, B., Anselm, E., Jeyaprakash, A.A., and Heun, P. (2019). Reconstituting Drosophila centromere identity in human cells. Cell reports, 2019 Oct 8;29(2):464-479.e5. doi: 10.1016/j.celrep.2019.08.067. PDF

Logsdon GA, Gambogi CW, Liskovykh MA, Barrey EJ, Larionov V, Miga KH, Heun P., Black BE., Human Artificial Chromosomes that Bypass Centromeric DNA. Cell. 2019 Jul 25;178(3):624-639.e19. doi: 10.1016/j.cell.2019.06.006. PDF

 Kyriacou, E. and P. Heun, High-resolution mapping of centromeric protein association using APEX-chromatin fibers.Epigenetics Chromatin, 2018. 11(1): p. 68. PDF

 Bobkov, G.O.M., N. Gilbert, and P. Heun, Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation. J Cell Biol, 2018. 217(6): p. 1957-1972. PDF

 Anselm, E., et al., Oligomerization of Drosophila Nucleoplasmin-Like Protein is required for its centromere localization.Nucleic Acids Res, 2018. 46(21): p. 11274-11286. PDF

 Barrey, E.J. and P. Heun, Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishment. Prog Mol Subcell Biol, 2017. 56: p. 193-212. PDF

Logsdon, G.A., et al., Both tails and the centromere targeting domain of CENP-A are required for centromere establishment. J Cell Biol, 2015. 208(5): p. 521-31. 

Padeken, J. and P. Heun, Nucleolus and nuclear periphery: velcro for heterochromatin. Curr Opin Cell Biol, 2014. 28: p. 54-60.

Barth, T.K., et al., Identification of novel Drosophila centromere-associated proteins. Proteomics, 2014. 14(19): p. 2167-78.

Thomae, A.W., et al., A pair of centromeric proteins mediates reproductive isolation in Drosophila species. Dev Cell, 2013.27(4): p. 412-24.

Padeken, J., et al., The nucleoplasmin homolog NLP mediates centromere clustering and anchoring to the nucleolus. Molecular cell, 2013. 50(2): p. 236-49.

Olszak, A.M., et al., Heterochromatin boundaries are hotspots for de novo kinetochore formation. Nature cell biology, 2011.13(7): p. 799-808.

Mendiburo, M.J., et al., Drosophila CENH3 is sufficient for centromere formation. Science, 2011. 334(6056): p. 686-90.